Oklahoma State Beats Colorado 57-24 as Mestemaker Throws Four Touchdowns

Colorado led 24-23 at halftime in Stillwater and did not score again. Oklahoma State ran off 34 straight second half points to beat the Buffaloes 57-24 on Saturday night, October 24, 2026, at Boone Pickens Stadium, in a homecoming game that turned from a shootout into a rout.

Drew Mestemaker threw for 386 yards and four touchdowns for Oklahoma State, with no interceptions. Caleb Hawkins added 120 rushing yards. The win took Oklahoma State to 5-2 overall and 3-1 in the Big 12. Colorado fell to 2-5 and 0-4 in the Big 12, in the Buffaloes' first trip to Stillwater since 2009.

A first half with no defence in sight

The teams combined for 591 yards before halftime. Mestemaker hit Miles Coleman for a 47 yard touchdown on the third play of the game, but Colorado answered with two Isaac Wilson touchdown passes, to JaQuail Smith and to DeAndre Moore Jr. from 15 yards in the final seconds of the first quarter, for a 14-7 lead.

Sam Keltner kept Oklahoma State close with field goals of 47, 30 and 41 yards. Mestemaker found Justin Bowick for a 15 yard touchdown after the pair connected for 52 yards on the same drive. Wilson scored on a short quarterback sneak for Colorado, and a 46 yard Colorado field goal made it 24-20 before Keltner's third field goal closed the half at 24-23. Wilson was 14 of 16 for 222 yards at the break. Mestemaker was 12 of 18 for 264.

Four turnovers end it

The second half opened with the play that changed the game. Wilson lost a fumble on the first play of the third quarter, Quinton Hammonds recovered at the Colorado 13, and Mestemaker threw a short touchdown pass for a 30-24 lead Oklahoma State never gave back. William Mason ran in a 3 yard touchdown after a 39 yard Hawkins run, and it was 37-24 by the end of the third quarter.

Wilson threw three interceptions in the second half. LaDainian Fields caught two of them, returning the second 36 yards to the Colorado 9 yard line in the fourth quarter. Keltner added a 21 yard field goal, Mestemaker hit Wyatt Young for a 28 yard touchdown, and Oklahoma State kept scoring late to reach 57. True freshman Kaneal Sweetwyne replaced Wilson at quarterback for Colorado in the fourth quarter.

Colorado scored on four of five first half possessions and on none after halftime. The result also flipped the last meeting between the schools: Colorado won 52-0 in Boulder in 2024, and this time Oklahoma State scored 57 of its own, 34 of them unanswered after the break.